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Contributor Information

  • Name Karen Pulford
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-TAL1 [2TL242]
  • Clone: 2TL242
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Description: TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia.
  • Immunogen: Recombinant TAL-1 protein
  • Isotype: IgG1 kappa
  • Research area: Cancer; Cell biology; Developmental biology; Genetics; Stem cell biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: TAL1 (SCL; TCL5)
  • Target background: TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia.

Application Details

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Chetty et al. 1997. J Pathol. 181(3):311-5. PMID: 9155718.
  • •  TAL-1 protein expression in vascular lesions.
  • •  Chetty et al. 1996. J Pathol. 178(3):311-5. PMID: 8778337.
  • •  An immunohistochemical study of TAL-1 protein expression in leukaemias and lymphomas with a novel monoclonal antibody, 2TL 242.
  • •  Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
  • •  Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
  • •  Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
  • •  Expression of TAL-1 proteins in human tissues.