ANTIBODIES
Contributor Information
- Name Karen Pulford
- Institute University of Oxford
Tool Details
- Tool name: Anti-Cytokeratin [K20]
- Clone: K20
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 46-67 kDa
- Application: IHC ; IHC ; WB
- Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles.
- Immunogen: Hair keratin
- Isotype: IgG2a kappa
- Research area: Cancer; Cell biology; Cell signaling and signal transduction
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Cytokeratins of 46, 48, 50, 55, 56, 56.5, 59, 61, 62, 64, 65, 66 and 67 kDa
- Target molecular weight: 46-67 kDa
- Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles.
Application Details
- Application: IHC ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Pulford et al. 1985. Histopathology. 9(8):825-40. PMID: 2414204.
- • Gatter et al. 1985. Histopathology. 9(8):805-23. PMID: 2414203.
- • The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders.
- • Human lung tumours: a correlation of antigenic profile with histological type.
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