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Contributor Information

  • Name Jacqueline Cordell
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-Biotin [BK-1/39] mAb
  • Clone: BK-1/39
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Gastric
  • Application: IHC ; IHC
  • Description: Anti-Biotin antibodies can be used to detect both biotinylated proteins and nucleic acids. Biotin is a water-soluble vitamin, generally classified as a B-complex vitamin. After the initial discovery of biotin, nearly forty years of research were required to establish it as a vitamin. Biotin is required by all organisms but can only be synthesized by bacteria, yeasts, molds, algae, and some plant species.
  • Immunogen: Biotin conjugated to keyhole limpet haemocyanin
  • Isotype: IgG1
  • Research area: Cancer; Cell biology; Cell signaling and signal transduction; Tags and cell markers; Metabolism
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Biotin
  • Target background: Anti-Biotin antibodies can be used to detect both biotinylated proteins and nucleic acids. Biotin is a water-soluble vitamin, generally classified as a B-complex vitamin. After the initial discovery of biotin, nearly forty years of research were required to establish it as a vitamin. Biotin is required by all organisms but can only be synthesized by bacteria, yeasts, molds, algae, and some plant species.

Application Details

  • Application: IHC ; IHC

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Documentation

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References

  • •  de Lima et al. 2012. Braz J Microbiol. 43(1):393-404. PMID: 24031845.
  • •  Epstein-Barr virus-associated gastric carcinoma in Brazil: comparison between in situ hybridization and polymerase chain reaction detection.
  • •  Hirokawa et al. 2010. Diagn Cytopathol. 38(12):890-6. PMID: 20091902.
  • •  Hirokawa et al. 2010. Diagn Cytopathol. 38(12):890-6. PMID: 20091902.
  • •  Cribriform-morular variant of papillary thyroid carcinoma--cytological and immunocytochemical findings of 18 cases.
  • •  Kojc et al. 2005. Hum Pathol. 36(1):16-21. PMID: 15712177.
  • •  Expression of CD34, alpha-smooth muscle actin, and transforming growth factor beta1 in squamous intraepithelial lesions and squamous cell carcinoma of the larynx and hypopharynx.
  • •  Kato et al. 2004. J Pathol. 203(3):814-21. PMID: 15221941.
  • •  Possible linkage between specific histological structures and aberrant reactivation of the Wnt pathway in adamantinomatous craniopharyngioma.
  • •  Xu et al. 2003. J Pathol. 199(1):58-67. PMID: 12474227.
  • •  Cribriform-morular variant of papillary thyroid carcinoma: a pathological and molecular genetic study with evidence of frequent somatic mutations in exon 3 of the beta-catenin gene.
  • •  Lu et al. 2000. J Oral Pathol Med. 29(9):445-51. PMID: 11016687.
  • •  Immunohistochemical study of the distribution of endogenous biotin and biotin-binding enzymes in ductal structures of salivary gland tumours.
  • •  Nakatani et al. 1998. Am J Surg Pathol. 22(4):399-411. PMID: 9537466.
  • •  Pulmonary adenocarcinomas of the fetal lung type: a clinicopathologic study indicating differences in histology, epidemiology, and natural history of low-grade and high-grade forms.
  • •  Umemura et al. 1996. Pathol Int. 46(2):122-9. PMID: 10846559.
  • •  'Magentosis' in human lactating breast: a mode of cell death accumulating single-stranded DNA stretches or breaks.
  • •  Arnholdt et al. 1991. Virchows Arch B Cell Pathol Incl Mol Pathol. 61(2):75-80. PMID: 1683723.
  • •  Receptor-mediated processing of epidermal growth factor in the trophoblast of the human placenta.