Product Image

Contributor Information

  • Name J. Rhodes
  • Institute University of Liverpool

Tool Details

  • Tool name: Anti-Mucin [Cam 17.1]
  • Clone: Cam 17.1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Pancreatic cancer
  • Application: ELISA ; FACS ; IHC ; IP
  • Description: CAM 17.1 is an antimucin monoclonal antibody which can be used for serological diagnosis of pancreatic cancer.
  • Immunogen: Coll2-23 colorectal cancer cells and live PC/AA polyposis coli cells.
  • Isotype: IgM kappa
  • Research area: Cancer; Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: Mucin (Colonic and pancreatic)
  • Target background: CAM 17.1 binds to a sialic-acid-containing determinant of mucin, probably sialyl-I, which epitope shows wide distribution throughout the gastro-intestinal tract.

Application Details

  • Application: ELISA ; FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Eccleston et al. 1998. Digestion. 59(6):665-70. PMID: 9813391.
  •   Pancreatic tumour marker anti-mucin antibody CAM 17.1 reacts with a sialyl blood group antigen, probably I, which is expressed throughout the human gastrointestinal tract.
  •   Yiannakou et al. 1997. Lancet. 349(9049):389-92. PMID: 9033465.
  •   Prospective study of CAM 17.1/WGA mucin assay for serological diagnosis of pancreatic cancer.
  •   Gansauge et al. 1996. Br J Cancer. 74(12):1997-2002. PMID: 8980403.
  •   CAM 17.1--a new diagnostic marker in pancreatic cancer.
  •   Parker et al. 1992. Cancer. 70(5):1062-8. PMID: 1515982.
  •   A new enzyme-linked lectin/mucin antibody sandwich assay (CAM 17.1/WGA) assessed in combination with CA 19-9 and peanut lectin binding assay for the diagnosis of pancreatic cancer.