ANTIBODIES

Contributor Information
- Name J. Rhodes
- Institute University of Liverpool
Tool Details
- Tool name: Anti-Mucin [Cam 17.1]
- Clone: Cam 17.1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Cancer type: Pancreatic cancer
- Application: ELISA ; FACS ; IHC ; IP
- Description: CAM 17.1 is an antimucin monoclonal antibody which can be used for serological diagnosis of pancreatic cancer.
- Immunogen: Coll2-23 colorectal cancer cells and live PC/AA polyposis coli cells.
- Isotype: IgM kappa
- Research area: Cancer; Cell signaling and signal transduction
- For Research Use Only
Target Details
- Target: Mucin (Colonic and pancreatic)
- Target background: CAM 17.1 binds to a sialic-acid-containing determinant of mucin, probably sialyl-I, which epitope shows wide distribution throughout the gastro-intestinal tract.
Application Details
- Application: ELISA ; FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Eccleston et al. 1998. Digestion. 59(6):665-70. PMID: 9813391.
- • Pancreatic tumour marker anti-mucin antibody CAM 17.1 reacts with a sialyl blood group antigen, probably I, which is expressed throughout the human gastrointestinal tract.
- • Yiannakou et al. 1997. Lancet. 349(9049):389-92. PMID: 9033465.
- • Prospective study of CAM 17.1/WGA mucin assay for serological diagnosis of pancreatic cancer.
- • Gansauge et al. 1996. Br J Cancer. 74(12):1997-2002. PMID: 8980403.
- • CAM 17.1--a new diagnostic marker in pancreatic cancer.
- • Parker et al. 1992. Cancer. 70(5):1062-8. PMID: 1515982.
- • A new enzyme-linked lectin/mucin antibody sandwich assay (CAM 17.1/WGA) assessed in combination with CA 19-9 and peanut lectin binding assay for the diagnosis of pancreatic cancer.