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Contributor Information

  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-HLADRb [TDR 31.1]
  • Clone: TDR 31.1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 29 kDa
  • Application: ELISA ; FACS ; RIA
  • Description: TDR 31.1 can be used for the identification of class II HLA molecules.
  • Immunogen: Ia fraction from Jy human B lymphoblastoid cell line. Class II from JY human B lymphoblastoid cell line.
  • Isotype: IgG1
  • Research area: Immunology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Human Leukocyte Antigen DR, beta chain, monomorphic.
  • Target molecular weight: 29 kDa
  • Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).

Application Details

  • Application: ELISA ; FACS ; RIA

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -20°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  de Kretser et al. 1982. Eur J Immunol. 12(3):214-21. PMID: 6178597.
  • •  Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis.
  • •  Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
  • •  Monoclonal antibodies for analysis of the HLA system.