ANTIBODIES

Contributor Information
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-HLADRa [TAL 1B5]
- Clone: TAL 1B5
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 33 kDa
- Application: IHC ; ELISA ; FACS ; IHC ; IF ; RIA ; WB
- Description: TAL 1B5 may be used for HLA typing.
- Immunogen: Bristol 8 separated alpha chain preparation
- Isotype: IgG1
- Research area: Immunology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Human Leukocyte Antigen DR, alpha subunit
- Target molecular weight: 33 kDa
- Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).
Application Details
- Application: IHC ; ELISA ; FACS ; IHC ; IF ; RIA ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
References
- • Roher et al. 2013. PLoS One. 8(3):e59735. PMID: 23555764.
- • Bapineuzumab alters a? composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy.
- • Chung et al. 2012. Int J Cancer. 131(3):E227-35. PMID: 22174092.
- • Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer.
- • van Dongen et al. 2010. Int J Cancer. 127(4):899-909. PMID: 20013807.
- • Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors.
- • Thomas et al. 1988. J Pathol. 154(4):353-63. PMID: 2455029.
- • HLA-D region alpha-chain monoclonal antibodies: cross-reaction between an anti-DP alpha-chain antibody and smooth muscle.
- • Adams et al. 1983. Immunology. 50(4):613-24. PMID: 6197354.
- • Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.