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Contributor Information

  • Name Julian Gannon
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-CyclinB2 [X121.10]
  • Alternate names: Cyclin B2; HsT17299
  • Clone: X121.10
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Xenopus laevis
  • Host: Mouse
  • Application: WB ; IHC ; IP ; WB
  • Strain: Balb/c
  • Description: X121.1 may be used to immunoprecipitate active CDK1 complexes.
  • Immunogen: Xenopus laevis Cyclin B2
  • Isotype: IgG1
  • Research area: Cell biology; Genetics
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Cyclin B2
  • Target background: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs).

Application Details

  • Application: WB ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.91 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Integrative module analysis of HCC gene expression landscapes
  • •  Li et al. 2020. Exp Ther Med. 19(3):1779-1788. PMID: 32104233.
  • •  Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis.
  • •  Activation of Xenopus eggs by the kinase inhibitor 6-DMAP suggests a differential regulation of cyclin B and p39(mos) proteolysis.