Product Image

Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Fibrin [UC45]
  • Clone: UC45
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 45 kDa
  • Application: IF ; FACS ; IF ; IP ; RIA
  • Strain: Balb/c
  • Description: Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a "mesh" that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.
  • Immunogen: Human acute monoblastic leukemia cells.
  • Isotype: IgM
  • Research area: Tissue-specific biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Fibrin alpha chain
  • Target molecular weight: 45 kDa
  • Target background: Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a "mesh" that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.

Application Details

  • Application: IF ; FACS ; IF ; IP ; RIA

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-Human APOE3 [APO3.1]

#160764
Product Image

Anti-AvW-4 [AvW-4]

#155102
Product Image

Anti-CD134 (OX40) [OX86]

#156620

References

  • •  Wu et al. 2013. Am J Nucl Med Mol Imaging. 3(5):446-55. PMID: 24116353.
  • •  Molecular MRI of atherosclerotic plaque progression in an ApoE(-/-) mouse model with a CLT1 peptide targeted macrocyclic Gd(III) chelate.
  • •  Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.
  • •  Monoclonal antibodies differentiating between monocytic and nonmonocytic variants of AML.
  • •  Hogg et al. 1983. J Exp Med. 157(2):473-85. PMID: 6822786.
  • •  Human monocytes are associated with the formation of fibrin.
  • •  Hogg et al. 1981. Cell. 24(3):875-84. PMID: 6788378.
  • •  Monoclonal antibody with specificity for monocytes and neurons.