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Anti-HPV16E7 [TVG 701Y] mAb

Cat. #151170

Tool name: Anti-HPV16E7 [TVG 701Y] mAb
Alternate names: Anti-Human Papillomavirus 16 (E7) antibody [TVG 701Y]; Anti-HPV16E7 [TVG 701Y]; HPV16 E7; Protein E7; E7; HPV antibody
Clone: TVG 701Y
Tool type: Antibodies
Tool sub-type: Primary antibody
Class: Monoclonal
Conjugate: Unconjugated
Reactivity: Human papilloma virus
Host: Mouse
Cancer type: Gynaecologic cancer
Application: ELISA ; FACS ; IHC ; IF ; WB
Strain: Balb/c
Description: Tumour antigens are proteins found in tumour cells and recognised by cellular or humoral effectors of the immune system. Tumour antigens are useful in identifying cancer cells, they also can be leveraged as targets in cancer therapy.

Anti-Human Papillomavirus 16 (E7) antibody [TVG 701Y] also known as Anti-HPV16E7 [TVG 701Y] is an antibody against a tumour-specific antigen (TSA). TSA's are restricted to tumours and are not found in healthy cells. Anti-HPV16E7 [TVG 701Y] is a monoclonal antibody against HPV16E7.

The human papilloma virus (HPV) family of DNA tumour viruses includes HPV-16 and HPV-18. These are associated with a large proportion of cervical cancer cases. E7 is the major transforming protein of human papillomavirus type 16 (HPV16).

The immunogen is HPV 16 E7 synthesised from S. pombe.
Immunogen: HPV 16 E7 synthesised from S. pombe
Isotype: IgG2a
Research area: Cancer; Microbiology
Myeloma used: P3/NS1/1-Ag4.1

Target: Human Papilloma Virus-16 early protein 7 (HPV16 E7)
Target background: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively.

£ 300
This fee is applicable only for non-profit organizations

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