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Contributor Information

  • Name Fiona Watt
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Involucrin [SY8]
  • Clone: SY8
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Dog ; Human ; Pig ; Primate
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: SY8 is useful for studies of changes in involucrin expression in pathological studies.
  • Immunogen: Purified involucrin from human keratinocytes.
  • Isotype: IgG1
  • Research area: Cancer; Cell signaling and signal transduction
  • Myeloma used: P3X63Ag8

  • For Research Use Only

Target Details

  • Target: Involucrin
  • Target background: Involucrin is a protein precursor of the epidermal cornified envelope and a differentiation marker of human keratinocytes.

Application Details

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Howie et al. 2011. PLoS Pathog. 7(8):e1002211. PMID: 21901101.
  • •  Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.
  • •  Hudson et al. 1992. Hybridoma. 11(3):367-79. PMID: 1500072.
  • •  Characterisation of eight monoclonal antibodies to involucrin.