ANTIBODIES

Contributor Information
- Name John Marshall
- Institute Queen Mary University of London
Tool Details
- Tool name: Anti-CD44 [P2A1]
- Alternate names: CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP9 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
- Clone: P2A1
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 95 kDa
- Application: FACS ; IHC ; IF ; IP
- Description: CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.
- Immunogen: Ocular melanoma cell line (V+B2)
- Isotype: IgG2a
- Research area: Cell biology; Cancer; Cell signaling and signal transduction; Immunology
- For Research Use Only
Target Details
- Target: CD44
- Target molecular weight: 95 kDa
- Target background: CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.
Application Details
- Application: FACS ; IHC ; IF ; IP
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.
- • Glatt et al. 2016. Mol Pharm. :. PMID: 27079967.
- • Bains et al. 2002. Fertil Steril. 78(2):307-12. PMID: 12137867.
- • Human sperm cells express CD44.
- • Nath et al. 1999. Immunology. 98(2):213-9. PMID: 10610356.
- • Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin.