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Contributor Information

  • Name John Marshall
  • Institute Queen Mary University of London

Tool Details

  • Tool name: Anti-CD44 [P2A1]
  • Alternate names: CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP9 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
  • Clone: P2A1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 95 kDa
  • Application: FACS ; IHC ; IF ; IP
  • Description: CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.
  • Immunogen: Ocular melanoma cell line (V+B2)
  • Isotype: IgG2a
  • Research area: Cell biology; Cancer; Cell signaling and signal transduction; Immunology

  • For Research Use Only

Target Details

  • Target: CD44
  • Target molecular weight: 95 kDa
  • Target background: CD44 is a broadly distributed receptor that binds hyaluronan. CD44 splice variants are associated with metastasis.

Application Details

  • Application: FACS ; IHC ; IF ; IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.
  •   Glatt et al. 2016. Mol Pharm. :. PMID: 27079967.
  •   Bains et al. 2002. Fertil Steril. 78(2):307-12. PMID: 12137867.
  •   Human sperm cells express CD44.
  •   Nath et al. 1999. Immunology. 98(2):213-9. PMID: 10610356.
  •   Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin.