ANTIBODIES
Contributor Information
- Institute Queen Mary University of London
Tool Details
- Tool name: Anti-Mast Cell [MCG35]
- Clone: MCG35
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: MCG25 is useful for mast cell identification in immunological reactions and hypersensitivity diseases e.g. allergy and asthma. The antigen is found in granule components of mast cells and may also be found intracytoplasmically in human mature small enterocytes, liver parenchymal cells and kidney proximal tubule epithelial cells.
- Immunogen: Spleen cells and bone marrow cells (erythrocyte depleted) from a patient with systemic mastocytosis. The bone marrow preparation consisted of 50% typical mast cells.
- Isotype: IgG1 kappa
- Research area: Tissue-specific biology
- Myeloma used: P3X63Ag8.653
- For Research Use Only
Target Details
- Target: Mast cell marker
- Target background: MCG25 is useful for mast cell identification in immunological reactions and hypersensitivity diseases e.g. allergy and asthma. The antigen is found in granule components of mast cells and may also be found intracytoplasmically in human mature small enterocytes, liver parenchymal cells and kidney proximal tubule epithelial cells.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Rimmer et al. 1987. Clin Exp Immunol. 68(3):712-8. PMID: 3308221.
- • Origin of human mast cells studied by dual immunofluorescence.
- • Rimmer et al. 1984. J Clin Pathol. 37(11):1249-55. PMID: 6389604.
- • Human mast cells detected by monoclonal antibodies.
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