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Contributor Information

  • Name Walter Bodmer
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Leu2 [M236]
  • Clone: M236
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 32 kDa
  • Application: IHC ; IP ; RIA
  • Strain: Balb/c
  • Description: M236 is useful for the identification of cytotoxic/suppressor cell subpopulation in peripheral blood, elimination of cytotoxic/suppressor cell subpopulation from peripheral blood and bone marrow, elimination of some T cell leukaemias and blocking of cytotoxic activity.
  • Immunogen: MOLT 4 cell line.
  • Isotype: IgG1
  • Research area: Immunology; Stem cell biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Leu2 (CD8)
  • Target molecular weight: 32 kDa
  • Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.

Application Details

  • Application: IHC ; IP ; RIA

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  1st International Workshop on Human Leucocyte Differentiation Antigans (code T67), Paris, November 1982