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Contributor Information

  • Name Walter Bodmer
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-EpCAM [AUA1]
  • Clone: AUA1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 40 kDa
  • Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: AUA1 cross reacts with breast carcinomas, kidney tubules, tonsil crypt epithelium and cells in some serious effusions. This is a good antibody for characterisation of all epithelial cells.
  • Immunogen: LoVo cell line, a colon carcinoma cell line.
  • Isotype: IgG1
  • Research area: Cancer; Cell biology
  • Myeloma used: P3X63Ag8

  • For Research Use Only

Target Details

  • Target: Epithelial Cell Adhesion Molecule (EpCAM, CD326)
  • Target molecular weight: 40 kDa
  • Target background: AUA1 cross reacts with breast carcinomas, kidney tubules, tonsil crypt epithelium and cells in some serious effusions. This is a good antibody for characterisation of all epithelial cells.

Application Details

  • Application: ELISA ; FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.93mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Hsia et al. 2016. Proc Natl Acad Sci U S A. :. PMID: 27036009.
  •   Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers.
  •   Screening of carcinoma metastasis by flow cytometry: A study of 238 cases.
  •   Acosta et al. 2015. Cytometry B Clin Cytom. :. PMID: 26054018.
  •   Yeung et al. 2013. Br J Cancer. 108(10):2106-15. PMID: 23652304.
  •   Myofibroblast activation in colorectal cancer lymph node metastases.
  •   Yeung et al. 2010. Proc Natl Acad Sci U S A. 107(8):3722-7. PMID: 20133591.
  •   Cancer stem cells from colorectal cancer-derived cell lines.
  •   Gaster et al. 2009. Nat Med. 15(11):1327-32. PMID: 19820717.
  •   Matrix-insensitive protein assays push the limits of biosensors in medicine.
  •   Ntouroupi et al. 2008. Br J Cancer. 99(5):789-95. PMID: 18682708.
  •   Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.
  •   Shaw et al. 2008. Cancer Cell Int. 8:3. PMID: 18348720.
  •   Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling.
  •   Moss et al. 1988. Lung Cancer. 4, 76-78.
  •   Epenetos et al. 1982. Lancet. 2(8306):1004-6. PMID: 6127499.
  •   Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions.
  •   Epenetos et al. 1982. Br J Cancer. 46(1):1-8. PMID: 7104190.
  •   Detection of human cancer in an animal model using radio-labelled tumour-associated monoclonal antibodies.