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Contributor Information

  • Name Mike Waterfield
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Thy1 [aThy-1A1]
  • Clone: aThy-1A1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IP
  • Description: Monoclonal antibody directed against Thy-1 thymocyte antigen.
  • Immunogen: Purified Thy-1.
  • Immunogen UniProt ID: P04216
  • Isotype: IgG2a
  • Research area: Cell biology; Cancer; Immunology; Neurobiology; Stem cell biology

  • For Research Use Only

Target Details

  • Target: Thy1 (CDw90)
  • Target background: Thy-1 is a GPI-anchored glycoprotein expressed in the brain, thymocytes and T lymphocytes. Anti-thy-1A1 has use in bone marrow purging. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons.

Application Details

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Stocco et al. 2019. Front Cell Dev Biol. 7:323. PMID: 31921840.
  • •  Prado et al. 2015. BMC Vet Res. 11:281. PMID: 26555093.
  • •  Favaron et al. 2014. PLoS One. 9(2):e95575. PMID: 24918429.
  • •  Cotmore et al. 1981. Eur J Immunol. 11(8):597-603. PMID: 7274325.
  • •  Purification of Thy-1-related glycoproteins from human brain and fibroblasts: comparisons between these molecules and murine glycoproteins carrying Thy-1.1 and Thy-1.2 antigens.